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But centuries ago, when tobacco and its use by Indigenous communities were first discovered during Christopher Columbus' expeditions to the Americas, the plant was warmly welcomed in Europe for its pleasurable and purported curative properties

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(Australian data published last year from the very large 45 and Up cohort study found that up to two in three long-term smokers were likely to die from a smoking-caused disease.) Two just-released papers promise to further ignite debate about these two central pillars of the case being made for these putative harm-reduction products