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It is worth noting at the outset that a lot of experiments involving the use of animals are so poorly designed that their results are meaningless

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Fundamentally, the public health challenge and the charge to policy development can be framed as balancing the potential use of e-cigarettes as a new technology to reduce the use of combustible tobacco products against the possibility of expanding tobacco use among non-using youth and young adults, long-term former smokers, and other vulnerable populations (e.g., women of reproductive age and individuals with significant comorbidities, including those with mental health problems)

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Some products may need specific plain packaging requirements, for example hand-rolling tobacco pouches can have a re-sealable sticker and cigarette packets can have a lining