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3.6 Human MoAM orthologs are increased in emphysema patients To examine the observed link between MoAM, smoke-induced chronic inflammation and the development of pulmonary emphysema in humans, we performed enrichment analysis of the murine MoAM gene signature orthologs from the chronic smoke model across the BALF cell populations identified in our recently performed COPD study ( Figure 7A ) ( Figure 7A )