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Trial registration Similar content being viewed by others Introduction Metabolic syndrome (MetS) is defined as a cluster of cardiovascular risk factors (i.e., abdominal obesity, hyperinsulinaemia, atherogenic dyslipidemia, hypertension, hypercogauability) that increase the risk of developing co-existing coronary heart disease (CHD) and type 2 diabetes [1]

The Fatigue Severity Scale is heavily weighted toward physical aspects of primary MS fatigue, with 8 of 9 questions querying this domain

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What the Research Shows Increases muscle carnitine stores when paired with elevated insulin (carbohydrate intake facilitates this) Enhances fat oxidation during low-intensity work while sparing glycogen during high-intensity efforts Reduces lactate and ammonia accumulation post-exercise Lowers muscle damage markers The compound also shifts your acetyl-CoA/CoA ratio favorably