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78 Therefore, whether p53 induces ferroptosis by promoting GLS2 expression is worth further investigation

When the concentration of Ca 2+ in the cytoplasm reaches a certain level, the calcium storage pool in the endoplasmic reticulum also releases Ca 2+ , inducing ERS (89, 90)

References [1] Basile EJ, Launico MV, Sheer AJ

Methods Antibodies, cell lines and reagents The following antibodies, secondary antibodies and fluorophore-coupled streptavidin were used for monobody selection and yeast display binding assays: mouse anti-V5 (Thermo Fisher Scientific, MA5-15253) and FITC-coupled anti-mouse IgG (Sigma-Aldrich, F0257-5ML), streptavidin-DyLight650 (Thermo Fisher Scientific, 84547)

Glutathione is a most potent antioxidant produced in virtually all cells, which is more researched than any biological medicine (including vitamin c and any drug)