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NETs can promote apoptosis in cardiomyocytes via the autophagy pathway, and cause swelling of mitochondria in cardiomyocytes, depolarization of mitochondrial membrane potential, and increased production of mitochondrial ROS (153), resulting in an increased susceptibility to AF (152)

For example, CRT and other DAMPs can be used to enhance the efficacy of DC vaccines, or IL-10 signaling can be blocked to reverse the immunosuppressive microenvironment, thereby optimizing the anti-tumor immune response (210)

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Same medication, different measurement convenience

Biotin (1 mM in PBS, sterile filtered) was added to a final concentration of 50 M at the indicated timepoint, and cells were harvested 24 h after transfection