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Although ChP BMAL1 downregulation partially enhances astrocyte function, this effect is insufficient to significantly reduce cortical A plaque deposition

The GPX family member glutathione peroxidase 4 (GPX4), the only isoenzyme that can reduce phospholipid hydroperoxide 6 , was considered one of the most important antioxidant enzymes in mammals 7

We immunoprecipitated OGDHc-E2 Lp glu adducts from HeLa cells treated with ML226, and then measured the levels of lipoate by immunoblot following short incubations of this immunoprecipitated OGDHc-E2 with purified ABHD11-Flag at 37 C

doi: 10.1016/j.pnpbp.2020.109868 3 CruzBFde Campos-CarliSMde OliveiraAMde BritoCBGarciaZMdo Nascimento ArifaRDet al

doi:10.1016/j.accpm.2018.04.003 17

Electronic supplementary material Additional file 1: Supplementary Material Model Details for A Mathematical Model of Glutathione Metabolism