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In particular, glutathione metabolism was highly enriched, which suggests that exogenous cystine may provide substrate for the pathway and play a critical role in restoring gentamicin susceptibility in drug-resistant strains

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Its metabolic functions include: Enhanced immune function Elimination of toxins Elimination of carcinogens Antioxidant cell protection Protections against ionizing radiation DNA synthesis and repair Protein synthesis Prostaglandin synthesis Amino acid transport Enzyme activation and regulation These functions can be summarized into three general categories: 1

Data availability The nuclear magnetic resonance and mass spectrometry data are provided in the Supplementary Information

(Gupta and Dhawan, 2021)

The RTqPCR mixture consisted of 5 L of SYBR Green Master Mix (Yeasen, Shanghai, China), 1 L of upstream primer, 1 L of downstream primer (with a final concentration of 0.2 M for each primer), and 2 L of cDNA, with enzyme-free water added to a final volume of 10 L