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2.2.3 DHODH pathway Dihydroorotate dehydrogenase (DHODH) is a mitochondrial inner membrane enzyme that plays a role in important metabolic pathways such as cytochrome P450, purine synthesis, and fatty acid metabolism (75, 76)

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sparing the active peptide ingredients from degradation by the proteolytic enzyme, pepsinogen

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This mechanism is distinct from how semaglutide (Wegovy) or tirzepatide (Zepbound) work

Sjgren A-K, Breitholtz K, Ahlberg E et al (2018) A novel multi-parametric high content screening assay in ciPTEC-OAT1 to predict drug-induced nephrotoxicity during drug discovery