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Dietary intervention studies have shown that the MedDiet, with or without caloric restriction, may induce weight loss in individuals with overweight and obesity ( Beyond examination of weight changes, studies have reported changes in inflammatory cytokines and a decrease in comorbidities in association with a MedDiet, even without weight loss

These diabetes-specific results mirror the pattern seen with CagriSema in REDEFINE 2, though direct comparison requires caution because the trial populations and designs differed

These happened due to neuronal atrophy and enhanced density of Nissl bodies and neurons of the hippocampus (70, 72)

Depletion of the GM leads to the loss of its mediated negative feedback control on BAs synthesis, reduced signaling to the FXR, elevated hepatic BAs concentrations, impaired biliary barrier function, and ultimately exacerbation of CLI [74]

Indian J Paediatr Dermatol

48 h after entering the low-pressure chamber, the rats were subjected to anesthesia through an intraperitoneal injection of 10% urethane at 1.5 g/kg, with placement in the supine position for fixation