Mal-Propionyl-PEG4-Val-Cit-PAB(m-PEG4) Size:50mg NCCC#CC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95%

NCCC#CC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Nature Communications

Product Name Thalidomide-C3-PEG3-OH Synonyms Thalidomide-4'-C3-PEG3-OH CAS Number n/a Related CAS Molecular Formula C22H28N2O8 Molecular Weight 448

Product Name Thalidomide-5'-O-PEG2-OH Synonyms CAS Number 2328212-84-4 Related CAS Molecular Formula C17H18N2O7 Molecular Weight 362

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Mal-Propionyl-PEG4-Val-Cit-PAB(m-PEG4) Size:50mg NCCC#CC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG4 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX