Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8) peg6 Abdul-Hadi

Abdul-Hadi

86 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCOCCOCC#C)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Contains an E3 ligase ligand with PEG linker and terminal amine

141 SMILES BrC1=CC=CC2=C1C(=O)C(C1CCC(=O)NC1=O)C2=O Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name DBCO-Maleimide Synonyms CAS Number 1395786-30-7 Related CAS Molecular Formula C25H21N3O4 Molecular Weight 427

Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8) peg6 Abdul-HadiSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. Derived from established