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4.2.2 Role of CBD in controlling protein expression Recent research has demonstrated that CBD can target the expression of Kelch-like ECH-associated protein 1 (Keap1) and Nrf2 in pulmonary artery smooth muscle cells, potentially boosting its antioxidant benefits in a model of pulmonary arterial hypertension (96)

Thus, necroptosis acts as a backup pathway for cell death during impairment of caspase-8-dependent apoptosis (Zhang et al., 2016

These factors not only influence tumor cell responses to chemotherapeutic drugs but also play a critical role in patient clinical prognosis

Hormone Therapy As we age, our hormones deplete naturally

doi: 10.1161/HYPERTENSIONAHA.113.00689

All of these could be related to the chemosensitizing role of antioxidants via prooxidant chemistry