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Injury-associated stem cells are imperative in orchestrating tissue regeneration, and dynamic adaptations of mitochondrial metabolism in the intestinal stem cell (ISC) niche are essential to ensure tissue homeostasis

10.3389/fcimb.2021.693051 47 WangJ.WangX.JiangM.LangT.WanL.DaiJ

In mouse models of lung injury and sepsis, EGCG administration significantly decreased MMP-9 levels in bronchoalveolar fluid and plasma, correlating with improved survival and reduced neutrophilic infiltration

mRNA was then isolated, fragmented and reverse-transcribed into the cDNA libraries with an mRNA-Seq preparation kit (Illumina, San Diego, CA, USA)

Among taxa predominating after ischemic injury, the relative abundance of Escherichia-Shigella , Clostridium_innocuum_group , Allobaculum , Romboutsia and Enterococcus correlated positively with levels of the six marker molecules (Figures 8A, C)

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