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[0124] Embodiment 117: The antibody according to any one of embodiments 1-8, wherein said antibody comprises a heavy chain variable region (VH) of an M25AGLF antibody and a light chain variable region (VL) of an M25AGLF antibody

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Concomitantly, the mitochondrial antioxidant enzymes superoxide dismutase (SOD2) and heme oxygenase-1 (HO-1) were elevated, suggesting an adaptive mitochondrial oxidative stress response ( Figure 4E )

Differential Diagnosis The differential diagnosis of such lesions includes cellular blue nevus, blue nevus with hypercellularity, the heavily pigmented epithelioid cell nevus, and regressed melanoma with prominent melanophage accumulation