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Glutathione serves as a coenzyme contributing a thiolate as a base in the isomerase mechanism, which also involves the active-site Tyr9 and Arg15

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& Gunton, J

Cells 10 , 540 (2021)

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As well, the amino acid transporter LAT (L-type amino acid transporter), which is involved in the uptake of many essential amino acids, was found to be overexpressed in many cancer cells