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This significance is usually explained by a spontaneous reduction in additional energy intake, a longer fasting period, and timing of food intake harmonized with circadian rhythms [123]

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I want to be honest about the evidence here, because this is an area where the research is genuinely mixed, and I think patients are better served by an accurate picture than a simplified one

They are not for human or veterinary use , not intended for diagnosis, treatment, cure, or prevention of any disease, and must be handled exclusively by qualified research professionals in controlled laboratory environments

2.2 Intestinal dysbiosis disrupts immune homeostasis and directly contributes to colitis The gut microbiota is essential for sustaining intestinal health by regulating epithelial barrier integrity (68) and modulating local and systemic immune function, often promoting a pro-inflammatory environment (68)