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For instance, exposure to H 2 O 2 stimulates PARP1 activation and subsequent AIFM1 nuclear translocation in glioma cells [156]

For the broader research-only context on the compounds above, the linked cluster guides cover each compound in depth

( 2 AX/H 2 AX, thereby promoting DNA repair and radioresistance ( Figure 3 )

20 On the other hand, nucleophilic addition of the thiolate anion (MeS - ) is feasible and likely spontaneous (G = 4.4 and 7.7 kcal/mol for 4 and 5 , respectively

Munc13-4STX7 small-molecule docking strategy AlphaFold2-Multimer was used to generate the Munc13-4STX7 complex by submitting full-length human protein sequences of Munc13-4 (UniProt Q70J99) and STX7 (UniProt O15400) with default settings to create five relaxed models

140 Nanoplastic exposure alters gut flora composition in mice, disrupts the gut barrier, leads to increased circulating LPS, and promotes liver cell pyroptosis and inflammation