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In this review, we discuss the role of TBK1 in immunological pathways involved in the development and maintenance of antibody responses, with particular emphasis on its potential relevance in the pathogenesis of humoral autoimmunity

The amount and type of melanin a person produces are influenced by genetics, environmental factors, and exposure to sunlight

In TME, DON is produced after enzymatic cleavage of JHU083 (Hanaford et al., 2019)

GalNAc is a high affinity ligand for asialoglycoprotein receptors (ASGPR) that are highly and specifically expressed on the surface of hepatocytes and, therefore, mediate rapid and efficient uptake of GalNAc-conjugated molecules into liver (Nair et al

ER stress is a typical trait in DbCM, and a recent study demonstrated that induction of ER stress by thapsigargin treatment in non-diabetic mice impairs mitochondrial respiration, may induce mPTP opening, and increases mitochondrial oxidative stress [137]

A deeper understanding of the gutkidney axis will pave the way for novel precision medicine strategies in DN treatment