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Similarly, studies recapitulating high-fat diets indicate the involvement of the zinc transporter ZIP7 in insulin signaling and glucose metabolism in skeletal muscle cells (266)

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It is employed in laboratory research examining growth hormone signalling, endocrine regulation and receptor-mediated cellular communication, making it a valuable analytical reagent for studies of peptide pharmacology and metabolic signalling

In the I-SPY2 trial, the cohort with HR+/HER2 tumors revealed that combining neoadjuvant pembrolizumab with chemotherapy effectively increases the pCR rate