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Additionally, SIRT1 modulates the activity of forkhead box O (FOXO) transcription factors, which activate the expression of enzymes involved in ROS detoxification, including SOD2 (superoxide dismutase 2) and catalase, thereby attenuating oxidative stress-induced apoptosis [51]

Bioaccumulation refers to the accumulation of any chemical component due to uptake by an organism from surrounding habitat (EPA 2003)

(PubMed) Wang L, Tian Z, Yang Q, et al

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10.1007/s10462-011-9289-8 98