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Hinokitiol-induced decreases of tyrosinase and microphthalmia-associated transcription factor are mediated by the endoplasmic reticulum-associated degradation pathway in human melanoma cells

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In nucleated cells, their functions are not limited to apoptosis, and caspases have been demonstrated to be involved in the regulation of multiple RCDs and related mechanisms, including pyroptosis (caspase-1), necroptosis (caspase-8), mitotic catastrophe (caspase-2), and regulation of inflammation [4]