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TB-500 sequesters G-actin monomers, regulating actin polymerization and thereby controlling cytoskeletal dynamics essential for cell migration

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3.3.1 Gut microbiome dysbiosis in GD induces unbalanced neurotransmitters in the brain Neurotransmitters like serotonin [also known as 5-hydroxytryptamine (5-HT), dopamine (DA), and noradrenaline (NE)] have been implicated in the pathophysiology of depression for many years as essential components of the brains function

Notably, FDXR deficiency or overexpression combined with RSL3 and erastin led to the induction of ferroptosis, suggesting that FDXR is closely associated with the underlying induction mechanism

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