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[55] established a rat kidney stone model by injecting glyoxalate and found that the mitochondria in rat RTECs became smaller and increased in membrane density, and the mitochondria were severely damaged

Digestive system problems Nausea Mild diarrhea Cramping or gas 3

In MAFLD, impaired AMPK signaling (e.g., due to reduced VEGFB expression) enhances SREBP1c and Scd1 activity, promoting lipid synthesis and hepatic steatosis [82]

In previous studies, Fe has been linked to the development of T2DM via the formation of ROS in the Fenton reaction [113]

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