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Introduction Intrauterine inflammation (IUI) is the primary cause of spontaneous preterm birth and predisposes neonates to long-term sequelae, including adverse neurological outcomes, and accounting for approximately 35% of neonatal deaths in 2017 ( Pro-inflammatory stimulation causes changes in the maternal immune system and placental microenvironment, a process in which placental macrophages may play an important role

[4] Vitiello MV, Schwartz RS, Moe KE, Mazzoni G, Merriam GR

While the metabolic switch probably fulfills multiple functions in these cells, its different benefits are not entirely clear

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[DOI] [PubMed] [Google Scholar] 89.Pedersen N., Andersen N., Vgh Z., Jensen L., Ankersen D., Felding M., Simonsen M., Burisch J., Munkholm P

Targeting epigenetic and post-translational modifications of NRF2: key regulatory factors in disease treatment