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These approaches include modifications in the timing and combination of antibiotic administration, as well as the use of alternative agents such as furazolidone and minocycline to address resistance to metronidazole or clarithromycin

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When the tumor volume reached approximately 100 mm 3 , mice were administered M-NFX (5 mg/kg NFX-equivalent dose, intravenously injected), macrophages (M, intravenously injected), NFX (5 mg/kg, orally administered), and saline for seven times following random grouping