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Creatine supplementation has been extensively studied in these sports, consistently demonstrating improvements in maximal strength, power output, and muscle mass

doi:10.1016/j.bios.2017.09.008 115

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and non-effective when there were no changes in semen examination parameters or even deterioration

Similarly, Zhu et al.[372] employed folic acid-modified D--tocopherol (FT@XBP1) NPs to deliver X-Box binding protein 1 ( XBP1 ) targeting siRNA, which promoted macrophage polarization toward the M2 phenotype and enhanced the release of exosomes that inhibited the activation of HSCs

10.3389/fphar.2018.01120 156 LiC.DengX.ZhangW.XieX.ConradM.LiuY.et al (2019)