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For instance, LPS-induced TLR4 signaling involves the recruitment of TIRAP and MyD88, followed by activation of IRAK1 and IRAK4 with the assistance of TRAF6 (79)

doi:10.1097/MAO.0b013e31825d644a Chimirri S, Aiello R, Mazzitello C, et al

These typically resolve quickly without any intervention

Isolation of peripheral blood mononuclear cells (PBMCs) and single-cell suspensions was performed using Ficoll Paque Plus (Millipore Sigma) density gradient centrifugation