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[DOI] [PubMed] [Google Scholar] 137.Gan J., Ruan Q., He B., Zhu M., Shyu W.C., Humphreys W.G

Protein mislocalization and cytoplasmic aggregation are prominent features in both genetic and nongenetic ALS, leading to loss of essential cellular functions

These include constrained tissue sizes, difficulty in cell retrieval for downstream analysis, and, most critically, a limited volume of effluent for comprehensive molecular profiling (e.g., proteomics, metabolomics), which is essential for biomarker discovery and mechanistic studies (215218)

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However, this approach, which typically examines single-target mechanisms, diverges from the holistic and complex nature of TCM

Reports suggest the peptide may enhance fibroblast migration and proliferation, potentially contributing to faster granulation and re-epithelialization