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However, under electrophilic or oxidative stress, KEAP1 changes its structure and NRF2 dissociates from the complex, accumulates in the nucleus and induces the expression of its target genes involved in the antioxidant response, detoxification, metabolism and inflammation [11]

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Class I histone deacetylases (HDAC1-3) are histone lysine delactylases

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It helps reduce pigmentation, fade dark spots, age spots, acne marks and other blemishes