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In this context, we stated that we believed that the aprevo Cervical ACDF System may be similar to devices described by C1831 and therefore, the aprevo Cervical ACDF System may be appropriately described by C1831

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In particular, the E-domains were enriched in disorder-promoting amino acids, and by bioinformatic analyses, we demonstrated that the E-domains are IDRs, which were also confirmed by the limited proteolysis approach (Figs 1 and S1C)

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