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Loftus et al, 1997)

Procedure: Remove the desired strips from the aluminum foil bag after equilibration at room temperature for 10 minutes

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In a double-blind, randomized study, subjects administered 3 g of L-Arg three times a day for 6 months exhibited increased coronary blood flow in response to increased acetylcholine, which was explained by a decrease in the levels of plasma endothelin in the L-Arg-treated group compared with the placebo group (150)

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2,75 =19.23, P 30 is generally accepted as indicative of minimally acceptable in vivo PK