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(2019) 1,25-Dihydroxyvitamin D exerts an antiaging role by activation of Nrf2-antioxidant signaling and inactivation of p16/p53-senescence signaling, Aging Cell , 18 , e12951, Lu, D., Le, Y., Ding, J., Dou, X., Mao, W., and Zhu, J

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49 In a clinical study involving 71 patients with T2DM and vitamin D deficiency, participants were randomized to receive either weekly high-dose vitamin D supplementation (20,000 IU/week) or placebo for 12 weeks