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Tabernilla A, dos Santos RB, Pieters A, Caufriez A, Leroy K, van Campenhout R, Cooreman A, Gomes AR, Arnesdotter E, Gijbels E, Vinken M (2021) In vitro liver toxicity testing of chemicals: A pragmatic approach

When 2,3- DPG is bound to Hgb, the dissociation curve of Hgb is shifted to the right

In other words, the body did not release GH as a perfectly flat hormonal signal but retained a degree of physiological pulsatile secretion

2013;8(4) doi: 10.1371/journal.pone.0061013

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found that in a SAH rat model, ACSL4 expression significantly increased in EBI