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The combination of the CD38 mAb with an IMiD remarkably enhances NK cell-mediated ADCC by increasing the quantity and activity of NK cells, promoting the tumoricidal activity of macrophages, and enhancing CD38 mAb-mediated ADCP

[2] Ongoing research comparing various long-acting estrogen esters suggests that estradiol cypionate provides a favorable pharmacodynamic window, but head-to-head trials remain limited and further study could clarify dosing equivalencies in diverse patient populations

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