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doi: 10.1038/s41423-022-00902-0 42 MichaeloudesCBhavsarPKMumbySXuBHuiCKMChungKFet al

The practical guidance is the same as everywhere on this site: follow the documented protocol for the specific compound

(4) Single route of administration: the current preclinical animal studies and clinical human trials predominantly employ oral administration as the primary intervention method for BBR, with a notable lack of research on alternative delivery approaches such as transdermal absorption

Suppressive effect of short-chain fatty acids on production of proinflammatory mediators by neutrophils

LidburyBAKitaBLewisDPHaywardSLudlowHHedgerMPet al

However, these findings remain preliminary and highlight the need for more rigorous studies before clinical implementation