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Group 1 metals include arsenic and arsenic compounds, cadmium, and nickel compounds

This finding establishes a direct link between ferroptosis and coronary microvascular pathology

Although preclinical studies have yielded encouraging results, clinical validation through Phase I/II trials is essential to confirm their safety and efficacy in humans

In zebrafish, intracellular NAD(H) levels were shown to be reduced in the absence of Letm1, a conserved mitochondrial cation exchanger which follows diurnal rhythms together with NAMPT, the key enzyme in NAD + production (Dao et al

Iron metabolism and lipid generation, storage, and degradation are all closely associated with ferroptosis

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