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Description

Mutations in FOXO genes have been suggested to cause hyperglycemia and hyperlipidemia and may even increase the risk of carcinogenesis in test models

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Studies show the compound crosses the blood-brain barrier efficiently despite its peptide structure, achieving central nervous system concentrations sufficient for biological activity following systemic administration

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Parker, A

Figure 2: Changes in rotation asymmetry expressed as the percentage of the animals rotation in the direction of the damage relative to rotations in both directions