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But why does IQWiG work the way it does

Generally, the worst side effects for vitamins including B vitamins are diarrhea, nausea, rashes, and vomiting

In platelets from dogs with occult heartworm disease, increased platelet activation was observed, what indicates that the increase was not associated with infection severity and microfilariae burden (326)

You may notice slight swelling, redness or bruising following the injections, but these effects are temporary and dont generally interfere with any activities

However, the urge to move the limbs is reported by most, if not all, people with RLS

Those are research categories, not promises of cosmetic or therapeutic results