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Its properties make it suitable for techniques such as HPLC, mass spectrometry, and other research-based analytical methods

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Thereby, plasma drug concentrations and the therapeutic half-live may be reduced, necessitating dose adjustment (Cunningham 1982

While the principles of N-terminal acetylation and C-terminal amidation are well established in peptide chemistry, direct comparative studies evaluating the modified forms biological activity against the parent peptide have not yet been published

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In a neurotrophic activity assay, Dihexa was found to be 7 orders of magnitude more potent than BDNF