methionine restriction glutathione

methionine restriction glutathione and Cancer Biology Dietary methionine restriction in cancer

Name: methionine restriction glutathione and Cancer Biology Dietary methionine restriction in cancer
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Dietary methionine restriction in cancer development and antitumor immunity: Trends in Endocrinology & Metabolism Methionine restriction Association with redox homeostasis and implications on aging and diseases ScienceDirect Early adult methionine restriction reduces methionine sulfoxide and extends lifespan in Drosophila Nature Communications Methionine deficiency facilitates antitumour immunity by altering m6A methylation of immune checkpoint transcripts Gut Altered dietary methionine differentially impacts glutathione and methionine metabolism in long living growth hormone deficient Ames dwarf and wild type mice Longevity & Healthspan Springer Nature Link Effect of different levels of dietary methionine restriction on relieving oxidative stress and behavioral deficits in middle aged mice fed low , medium , or high fat diet ScienceDirect

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Although xCT expression is confined to the plasma membrane in normal tissues (36,39), it is upregulated in certain types of cancer, such as colorectal cancer, malignant glioma and non-small cell lung cancer, which increases cystine uptake (4042)

It was shown that this type of modification can form dimers of Kelch-like ECH-associated protein 1 (KEAP1) proteins, which in turn can activate nuclear factor erythroid 2-related factor 2 (Nrf2) transcription factor, and thereby promote the transcription of antioxidant genes [44]