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Liu et al., 2011)

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T-cell proliferation involving the CD28 pathway is associated with cyclosporine-resistant interleukin 2 gene expression

125 In addition, lactylation of -myosin heavy chain (-MHC) at K1897 maintains sarcomeric structure and alleviates heart failure by facilitating its interaction with Titin

Clinically, veterinary patients who suffer from heat stress have been shown to experience clinical signs that range in severity from mildly decreased feed intake and milk production (reported in dairy cows) to more severe consequences including altered immune responses [55] and death [56,57]

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