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We tested this idea using genetic and pharmacological inhibition of TS activity

Gastroenterology 2001

The percentage of subjects receiving OCA 25 mg that achieved the primary endpoint was 23.8% among those with baseline GLP-1 RA use, 21.6% of those who added a GLP-1 RA, and 22.4% in the overall ITT population, compared to 4.3%, 7.5%, and 9.6% receiving placebo, respectively (Figure 1)

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(no photo available) 96 tests $901 KT-7579 Aquaporin 3, Gill Blood Group (AQP3) ELISA Kit, Human For quantitative detection in human samples

Int Immunol 1:367372 Erdo SL, Schafer M (1991) Memantine is highly potent in protecting cortical cultures against excitotoxic cell death evoked by glutamate and N-methyl-D-aspartate