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pmid:26504249 27

GO and REACTOME pathway enrichment analysis results revealed that the upregulated genes were mainly enriched in multicellular organismal process, membrane, small molecule binding and extracellular matrix organization, whereas downregulated genes were mainly enriched in organonitrogen compound metabolic process, intracellular anatomical structure, catalytic activity and translation

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For gout, low-Zn 2+ -doped zinc ferrite nanoparticles exhibit dual anti-inflammatory and antioxidant effects by modulating NF-B/NLRP3 signaling and activating the Nrf2 pathway, thereby reducing joint inflammation and oxidative stress in murine models (Zhang et al., 2025)

34 Other genes overexpressed in BCBM cells, such as ADAM8 and SEMA4D, have also been shown to be regulators of BBB transmigration

Yousef, M.I