34 , 37 This comprehensive exploration of family, gender, and ethnicity deepens our understanding of the multifaceted factors contributing to premature graying, offering valuable insights into its diverse manifestations across populations (Table 1)
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Composed of c-Jun and c-Fos, AP-1 is activated by ROS and synergizes with NF-B to enhance pro-inflammatory factor transcription, while participating in the regulation of airway epithelial cell squamous metaplasia (27)
By scavenging both mitochondrial and extracellular ROS through redox and catalase-like activity, these nanoparticles reduce oxidative stress, alleviate hypoxia, and restore conditions favorable for endothelial cell function and angiogenesis
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