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, , , 5 7.5 pH , 5.5 pH , 7.0 pH .In certain embodiments, the pharmaceutical composition provided herein is an enteric coating, for example, an enteric coating that dissolves at a pH of about 5 to about 7.5, an enteric coating that dissolves at a pH of about 5.5 or higher, or dissolves at a pH of about 7.0 or higher

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Trials 8 , 21 (2007)

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Its small molecular size allows it to penetrate intestinal epithelial cells directly, which is why it has attracted research interest as an orally deliverable gut-targeted compound

The onset is uncertain and the range of symptoms is very wide