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[PubMed: 19567534] 55

Long-term use of proton-pump inhibitors has been found to decrease blood vitamin B 12 concentrations

[19] Pernicious anemia [edit] Pernicious anemia is a disease caused by an autoimmune response that produces antibodies that attack the parietal cells in the stomach lining, preventing them from creating intrinsic factor needed for the absorption of vitamin B 12

Bang P, Westgren M, Schwander J, Blum WF, Rosenfeld RG, Stangenberg M

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