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Li W-R, Zhang Z-Q, Yao J-W et al (2022a) Diallyl trisulfide attenuates Pseudomonas aeruginosa virulence via inhibiting quorum sensing

There is evidence that acrolein can activate the protein kinase C (PKC), which is responsible for the phosphorylation of the cytosolic subunits of the NADPH oxidase, promoting the assembly of the activated membrane complex [33, 55, 56, 86]

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Acknowledgments The authors gratefully acknowledge the use of the services and facilities of the Koc University Research Center for Translational Medicine (KUTTAM), funded by the Presidency of Turkey, Presidency of Strategy and Budget

Therefore, when modulating the gut microbiota to alter SCFA levels, it is crucial to simultaneously consider their bioavailability at both the local intestinal and systemic levels to avoid the metabolic burden caused by excess energy