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Particularly noteworthy, Cassia seed aqueous extract inhibits FASN expression via the AMPK/TFEB-mediated autophagy pathway ( /CPT-1A pathway ( 6 Limitations of preclinical evidence and appraisal of translational gaps While current clinical management of NAFLD primarily relies on lifestyle modifications and metabolic regulation interventionsincluding insulin sensitizers, antioxidants, and lipid-lowering agentsthese approaches can delay disease progression but rarely reverse hepatic steatosis and fibrosis

The IgG Solanezumab biosimilar antibody was obtained from Antibodies-online (Cat.# ABIN7487922, CAS 955085-14-0), the Goat anti-Rabbit IgG unconjugated control antibody was purchased from Invitrogen (Cat.# A27033)

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Exosome therapy offers several theranostics potentials in experimental studies, but there are still several practical issues that impede their clinical translation