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View Study [2]"Safety, tolerability, pharmacokinetics, and pharmacodynamics of cagrilintide with semaglutide" Enebo LB et al., 2021 Finding: Phase 1b trial demonstrated that combining cagrilintide with semaglutide 2.4mg resulted in up to 17.1% weight loss at 20 weeks, with the combination being well-tolerated

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Objective markers (IGF-1, metabolic panels, and where tested, biological age) typically show measurable improvement

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They activate some overlapping populations of neurons, but separate neurons, which, I think, is the basis for their additive effect